What should the paramedic do for a 66-year-old female who has chest pain after taking three doses of sublingual nitroglycerin with no relief?

Administering oxygen is crucial in this scenario, especially given that the patient is experiencing chest pain and has already taken multiple doses of sublingual nitroglycerin without relief. Oxygen therapy helps to ensure that the heart muscle receives adequate oxygen, which is vital in mitigating ischemic damage during a cardiac episode.

In cases of chest pain, particularly when associated with potential cardiac issues, providing supplemental oxygen can help alleviate discomfort and improve outcomes. The administration of oxygen is particularly important if there are signs of respiratory distress or if the patient is hypoxic, as impaired oxygenation can exacerbate the situation.

While reassessing vital signs, providing aspirin, and preparing for immediate transport are all important steps in managing a patient with chest pain, the priority is often to stabilize the patient by improving their oxygenation status first, especially when there is ongoing discomfort despite the nitroglycerin administration. This foundational step helps in creating a safer environment for further interventions and transport.